Nanofat does not has the capacity to build up a significant fat volume. The Indications for nanofat injection are different when compared with microfat grafting.
Usually, nanofat grafting is combined with other modalities such as sharp needle intradermal fat grafting (SNIF) to obtain a soft-tissue filling effect, where the nanofat is layered more fanwise in an intradermal level to enhance the skin quality. In some areas the results can take between 1-3 months to become evident, other areas such as dark circles of the eyes, a prolonged erythematous phase, can also sometimes be expected. Nano fat grafting is recommended for facial rejuvenation for facial wrinkle lines, lower eyelids, upper eyelids hallowing, brow, lips, perioral lines, Neck line, Lowe neck line also known as décolletage. It can also be used for cheek and temporal hallowing area in combination with micro fat grafting.